PMMA-collagen gel dermal filler post-marketing safety experience
نویسندگان
چکیده
منابع مشابه
Novel hyaluronic acid dermal filler: dermal gel extra physical properties and clinical outcomes.
BACKGROUND Dermal gel extra (DGE) is a new, tightly cross-linked hyaluronic acid (HA)-based dermal filler containing lidocaine engineered to resist gel deformation and degradation. OBJECTIVES To develop a firmer gel product (DGE) and compare the efficacy and safety of DGE with nonanimal stabilized HA (NASHA) for correction of nasolabial folds (NLFs). METHODS DGE physical properties were cha...
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Drug induced liver injury during drug development is evidenced by a higher incidence of serum alanine aminotransferase (ALT) elevations in treated versus placebo populations and termed an "ALT signal". We sought to quantify whether an ALT signal in pre-marketing clinical trials predicted post-marketing hepatotoxicity. Incidence of ALT elevations (ALT ≥ 3 times upper limits normal [× ULN]) for d...
متن کاملAutologous collagen dispersion (Autologen) as a dermal filler: clinical observations and histologic findings.
OBJECTIVE To assess the histologic behavior and clinical efficacy of autologous collagen dispersion (Autologen) in augmenting human dermis. SUBJECTS Adult patients of the Facial Plastic Surgery Clinic at The New York Eye and Ear Infirmary who were undergoing facial aesthetic surgery with skin excision. METHODS Five patients were injected intradermally with Autologen in one postauricular are...
متن کاملUnderstanding, avoiding, and managing dermal filler complications.
BACKGROUND Dermal fillers are increasingly being utilized for multiple cosmetic dermatology indications. The appeal of these products can be partly attributed to their strong safety profiles. Nevertheless, complications can sometimes occur. OBJECTIVE To summarize the complications associated with each available dermal filling agent, strategies to avoid them, and management options if they do ar...
متن کاملTreatment options for dermal filler complications.
The author contends that early adverse reactions to dermal fillers are caused by a superficial injection technique and that late adverse reactions result from unique patient responses. He has found all complications treatable with a correct dose of intralesional steroids or inconspicuous surgical entry. Here he provides guidelines for injection techniques and treatment for complications.
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ژورنال
عنوان ژورنال: International Journal of Women's Dermatology
سال: 2019
ISSN: 2352-6475
DOI: 10.1016/j.ijwd.2019.04.016